描述

Textbook of Diabetes
Third Edition
Editors:Clive Cockram, John Pickup, Gareth Williams
1649 illustrations
1520 pages
Hardback 063205915X
Price £250.00

‘Textbook of Diabetes is an extremely well organized, superbly edited, richly illustrated two-volume set from Britain… The chapters have logical beginnings and endings and are self-contained. Each begins with a summary of the chapter contents – a true summary, not a mere listing of the topics to be discussed… Until receiving this new text, I referred equally as often to Joslin’s Diabetes Mellitus (Williams and Wilkins 1994) and International Textbook of Diabetes (Wiley, 1997). If truth be told, Pickup and Williams’ Textbook of Diabetes is slightly easier to read because of the typeface and graphs. As I have less time than ever, this attention to detail will certainly make it as attractive as the other two.’
-JAMA, April 1998 (on the second edition)

‘The media, especially television, often offer programs on diabetes, and numerous books about diabetes are presented to to general practitioners, nurses, dieticians and specialists. While this is certainly the result of a growing interest in the subject and a greater demand for knowledge about it, one might wonder about the real need to another book about diabetes. Considering all this, the editorial success of the second edition of the Textbook of Diabetes seems even more spectacular. The reasons for this success are several. The ability of the editors and authors to present a comprehensive, concise, updated review of virtually all aspects of diabetes is a key factor… A second important reason for the success of this book lies in the presentation of the figures, illustrations, graphs and tables… The second edition of the Textbook of Diabetes appears seven years after the first edition, which was a great success. It is interesting to see that the editors were able to improve something that was already good.’
-New England Journal of Medicine, February 1998 (on the second edition)

‘What makes Pickup and Williams different from its equally heavy competitors is the beautiful layout with exceptionally clear figures and generous use of colour photographs. The general standard of all the chapters is high and several are outstanding.’
-Journal of the Royal College of Physicians, September 1997 (on the second edition)

‘Expanding the book has considerably improved it, and the new edition now constitutes a definitive text… It must now be the best large general text available on diabetes and I commend it highly to anyone with a career interest in clinical or academic diabetes, and to general endocrinologists who wish to keep in touch with developments in the field.’
-The Endocrinologist, July 1997 (on the second edition)

Pickup and Williams’ Textbook of Diabetes has established itself as the definitive reference work in the field, providing lucid, comprehensive coverage of the subject with full colour illustrations and beautiful presentation. The focus of the book is very much clinical, but throughout the coverage of basic science is strong and pervades most clinical components of the book. The significant advances that have occurred in our understanding of the disease are reflected in this new edition.

A total of 74 chapters are organised into 20 sections covering the all issues relating to the clinical management of the disease, from the historical context, normal physiology, pathogenesis of diabetes, diabetes complications, the practicalities of living with diabetes, the organisation of care and future developments.

The chapter list has been revised and updated to further refine the coverage of the second edition. At least a third of the contributors are new and have provided a wealth of fresh material to the book. All the other chapters have been thoroughly rewritten.
Please view sample pages from chapter 31 and chapter 75.

comprehensive coverage of clinical diabetes with a strong scientific perspective throughout

now established as THE reference work on diabetes

commended for its excellent layout and wealth of colour illustrations

this edition has a truely international outlook with its global list of contributors

the second edition won first prize in Medicine at the Medical Book of The Year, BMA Awards, and first prize in Advanced Edited Book category, RSM Awards, in 1997.

Contents

Section 1: Diabetes in its historical and social context

1. The history of diabetes

2. The diagnosis and classification of diabetes and impaired glucose tolerance

3. Type 1 diabetes: an overview

4. Type 2 diabetes: an overview

5. Epidemiology of type 1 diabetes

6. Epidemiology of type 2 diabetes

7. Health and social costs of diabetes

8. The challenge of diabetes in the developing world

Section 2: Normal metabolism

9. Normal metabolism: an overview

10. The anatomy, organisation and ultrastructure of the islets of Langerhans

11. The hormonal and neural control of endocrine pancreatic function

12. The structure and phylogeny of insulin

13. The biosynthesis and secretion of insulin

14. The insulin receptor and signalling mechanisms

Section 3: Pathogenesis of type 1 diabetes

15. Genetic factors in the pathogenesis of type 1 diabetes

16. Viruses in the pathogenesis of type 1 diabetes

17. Diet and other environmental factors

18. Immunology and histology of type 1 diabetes

19. Animal models of type 1 diabetes

Section 4: Pathogenesis of type 2 diabetes

20. Genetic factors in the pathogenesis of type 2 diabetes

21. Obesity and nutritional factors in the pathogenesis of type 2 diabetes

22. Insulin resistance in type 2 diabetes

23. B-cell defects and pancreatic abnormalities in type 2 diabetes

24. Maturity-onset diabetes of the young

25. Animal syndromes of type 2 diabetes

Section 5: Other types of diabetes

26. Drug-induced diabetes

27. Endocrine diseases and diabetes

28. Pancreatic disease and diabetes

29. Syndromes of severe insulin resistance

30. Insulinopathies and genetic syndromes and diabetes

Section 6: Metabolic disturbances of diabetes

31. Metabolic disturbances in diabetes

32. Acute metabolic complications of diabetes: diabetic ketoacidosis, hyperosmolar non-ketotic syndrome and lactic acidosis

33. Hypoglycaemia in diabetes

Section 7: Measurements in diabetes

34. Diabetic control and its measurement

35. Research methods in Diabetes

Section 8: General management issues in diabetes

36. Diet and lifestyle modification

37. Exercise in diabetes

38. Education of the diabetic patient

39. Drugs and diabetes

40. Infection and diabetes

41. Surgery in patients with diabetes

Section 9: Management of type 1 diabetes

42. Insulin pharmacology

43. Insulin treatment its complications

44. Alternative forms of insulin delivery

Section 10: Management of type 2 diabetes

45. Drug treatment of type 2 diabetes

Section 11: Mechanisms in chronic diabetes

46. The epidemiology of complications and the relationship to blood glucose control

47. The biochemical basis of microvascular disease

Section 12: Diabetic eye disease

48. Pathogenesis of diabetic retinopathy and cataract

49. The clinical features and management of diabetic eye disease

Section 13: Diabetic neuropathy

50. Pathogenesis of diabetic neuropathy

51. The clinical features and management of diabetic neuropathy

Section 14: Diabetic nephropathy

52. Pathogenesis of diabetic nephropathy

53. Clinical features and management of diabetic nephropathy

Section 15: Macrovascular disease

54. Lipid disorders in diabetes

55. Hypertension and diabetes

56. Cardiovascular disease in diabetes

Section 16: Other complications of diabetes

57. Foot problems in patients with diabetes

58. Sexual function in diabetic men and women

59. Gastrointestinal disorders in diabetes

60. The skin in diabetes

61. Bone and rheumatic disorders in diabetes

62. The central nervous system and diabetes

63. Psychological factors and diabetes

64. Psychiatric disorders and diabetes

Section 17: Diabetes in special groups

65. Pregnancy and diabetes

66. Diabetes in childhood and adolescence

67. Old age and diabetes

Section 18: Living with diabetes

68. Diabetes and lifestyle

69. Genetic counselling in diabetes

Section 19: Delivery and organization of diabetes care

70. The role of the hospital and role of general practice in diabetes care

71. The role of the diabetes specialist nurse

Section 20: Vignettes on future directions in diabetes research

72. Pancreas and islet transplantation

73. New drugs in the management of diabetes and its complications

74. Immunotherapy for the prevention of type 1 Diabetes

75. Stem cell therapy

76. Gene therapy

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