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Ascites and Renal Dysfunction in Liver Disease

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Ascites and Renal Dysfunction in Liver Disease
Second Edition
USA: Aug 2005
Edited By: Pere Ginès,
Pere Ginès, University of Barcelona School of Medicine
Vicente Arroyo, University of Barcelona School of Medicine
Juan Rodés, University of Barcelona School of Medicine
Robert W Schrier, University of Colorado School of Medicine, Denver, CO

There are a number of diseases, such as ascites, renal dysfunction, cirrhosis and hypertension where both the liver and the kidney are involved. In addition, both organs are very important in regulating extracellular fluid volume, and how they work together or don’t work together can affect circulation and the heart. There has been very little written in the literature on the interaction of the two organs. This book addresses that problem.

The first edition of Ascites and Renal Dysfunction in Liver Disease was published in January 1999 and received extremely positive reviews:

‘There is no doubt that this textbook is essential, even for confirmed practitioners’ Acta Gastro-enterologica Belgica

‘Current information regarding treatment and therapy for patients with cirrhosis and ascites is clearly and effectively presented by the top international experts within this field’ Scandinavian Journal of Gastroenterology

The second edition is entirely revised and updated and the contents place greater emphasis on therapy.

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Contents
Part 1 Regulation of Extracellular Fluid Volume and Renal and Splanchnic Circulation

1 Extracellualr fluid volume homeostasis

2 Physiology of the renal circulation

3 Physiology of the gastrointestinal circulation

Part 2 Factors Involved in the Pathogenesis of Renal Dysfunction and Ascites in Cirrhosis

4 The renin-angiotensin-Aldosterone system in cirrhosis

5 The sympathetic nervous system in cirrhosis

6 Atrial natriuretic peptide and other natriuretic factors in cirrhosis

7 Arachidonic acid metabolites and the kidney in cirrhosis

8 Nitric oxide and systemic and renal hemodynamic disturbances in cirrhosis

9 Endothelin and systemic, renal and hepatic hemodynamic disturbances in Cirrhosis

10 Carbon monoxide and the hemeoxygenase system in cirrhosis

Part 3 Systemic and Splanchnic Hemo-dynamic Abnormalities in Cirrhosis

11 The systemic circulation in cirrhosis

12 The splanchnic circulation in cirrhosis

13 Physiology of hepatic circulation in cirrhosis

14 Alterations of hepatic and splanchnic microvascular exchange in cirrhosis: local factors in the formation of ascites

15 The heart in cirrhosis

Part 4 Ascites and sodium retention in cirrhosis

16 Pathogenesis of sodium retention in cirrhosis. The arterial vasodilation hypotheses of ascites formation

17 Experimental Models of Cirrhosis and Ascites

18 Medical treatment of ascites in cirrhosis

19 Paracentesis for cirrhotic ascites

20 Transjugular intrahepatic portosystemic shunts – TIPS for the management of refractory ascites in cirrhosis

21 Prognosis of patients with cirrhosis and ascites

22 Liver transplantation for patients with cirrhosis

23 A Practical approach to treatment of patients with cirrhosis and ascites

24 Etiology, diagnosis, and managment of non-cirrhotic ascites

Part 5 Hyponatremia and water retention in cirrhosis

25 Pathogenesis of hyponatremia. The role of argenine vasopressin

26 Management of hyponatremia in cirrhosis

Part 6 Spontaneous bacterial peritonitis in cirrhosis

27 Pathogenesis of renal vasoconstriction in cirrhosis

28 Hepatorenal syndrome in cirrhosis: Clinical, diagnosis, and management

29 Glomerular disease in cirrhosis

30 Drug-induced renal failure in cirrhosis

31 Clinical disorders of renal function in acute liver failure

32 Renal dysfunction in obstructive jaundice

Part 7 Spontaneous bacterial peritonitis in cirrhosis

33 Experimental models of spontaneous bacterial peritonitis

34 Pathogenesis and clinical features of spontaneous bacterial peritonitis

35 Treatment and prohylaxis of spontaneous bacterial peritonitis

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