(已絕版)ECMO: Extracorporeal Cardiopulmonary Support in Critical Care, Red Book 4/E 2012

描述

ECMO: Extracorporeal Cardiopulmonary Support in Critical Care, Red Book
Gail M., Ed. Annich (Author)
Paperback: 537 pages
Publisher: EXTRACORPOREAL LIFE SUPPORT ORGANIZATION; 4 edition (June 15, 2012)

ECMO Extracorporeal Cardiopulmonary Support in Critical Care 4th Edition

Table of Contents

Dedication

Preface to the 4th Edition

I: Extracorporeal Life Support: An Overview

1 The History and Development of Extracorporeal Support

Biographical Beginnings: People

Propagation of ECMO

Perseverance: Adult ECMO Experience

References

2 Physiology of Extracorporeal Life Support

Physiology of Extracorporeal Life Support

Normal physiology

Pumps

Gas Exchange in Extracorporeal Life Support

Physiologic Principles in the Management of Extracorporeal Life Support

Managing the Patient on ECLS

Weaning and Decannulation

References

3 Cardiac Failure: Principles and Physiology

Introduction

Determinants of cardiac output

Compensated and Decompensated Cardiac Failure

Cardiac Function on ECMO

Summary

References

4 Acute Hypoxic Respiratory Failure in Children

Introduction

The Pathophysiology of Acute Lung Injury

Positive Pressure Ventilation and PEEP in the Management of ARDS

Ventilation Induced Lung Injury

Pulmonary Oxygen Toxicity

Epidemiology and Markers of Acute Lung Injury

The Development of a Lung Protective Ventilation Strategy

Algorithm for a Lung Protective Ventilation Strategy in ARF

Ventilation Strategy

Oxygenation Strategy

Alternative Ventilation Strategies for ARDS

High Frequency Ventilation

High Frequency Oscillatory Ventilation (HFOV)

Prone Position Ventilation

Adjuncts to Positive Pressure Ventilation

Inhaled Nitric Oxide (iNO)

NonInvasive Ventilation

Extra-Pulmonary Therapies in ARDS

Acute Hypoxic Respiratory Failure

Summary

References

5 Blood Biomaterial Surface Interaction During ECLS

Introduction

Normal Hemostasis

Coagulation Pathway Activation and Inflammatory Response

Activation of the Coagulation System during ECLS

References

6 The Registry of the Extracorporeal Life Support Organization

Introduction

History

Data Collection and Reporting

Implementation

Registry Data Summary

Summary

References

II: General Management and Outcomes

7 Preface to Sections II-V

Section II General Management and Outcomes:

Section III Patient Specific Management and Outcomes:

Section IV Other Uses for ECLS:

Section V Logistics and Legalities of ECLS:

8 The Circuit

Introduction

General principles of circuit design

Criteria for selecting circuit components

Circuit components

Pump types

Gas exchange devices

Commercial gas exchange devices

Circuit management

Refining circuit design: Simplicity and integrated systems

Summary: The circuit

References

9 Vascular Access for Extracorporeal Support

Introduction

Principles

Cannula Insertion for Neonatal ECLS

Cannula Insertion for Pediatric ECLS

Cannula Insertion for Adult ECLS

Transthoracic Cannulation

Cannulation Complications

References

10 Management of Blood Flow and Gas Exchange during ECLS

A Criteria for selecting circuit components

B Management during ECLS

C Ventilator management

References

11 Anticoagulation and Bleeding During ECLS

Anticoagulation

Clinical Consequences

Conclusions

References

12 Analgesia, Sedation, Neuromuscular Blockade, and Temperature Contro

Analgesia and Sedation

Pharmacology and ECLS

Indications for Sedation and Analgesia

Analgesia

Sedation

Neuromuscular Blockade

Delirium

Temperature Control

References

13 Renal Function and Renal Supportive Therapy during ECMO

Renal Function

Supporting Renal Function

Outcomes

Conclusions

References

14 Infections and ECMO

Epidemiology

Prophylaxis

Diagnosis of Infections while on ECMO

Surveillance

Discussion

References

15 Procedures on ECMO

Procedures Guidelines

Comments on Procedures on ECMO

Specific procedures

16 Weaning, Trialing and Futility

Weaning the Neonatal Patient

Trialing off ECMO

Futility

References

III: Patient Specific Management and Outcomes

17 Neonatal Respiratory ECLS

Introduction

Diseases Treated

Patient Selection Criteria

Contraindications

Modes of neonatal ECMO

ECMO details

Management during ECLS

Procedures

Complications

References

18 Congenital Diaphragmatic Hernia and ECMO

Introduction

Diagnosis

Management

ECMO

Summary

References

19 ECMO for Pediatric Respiratory Failure

Selection Criteria

Patient Population

Unique Patient Populations for ECLS Use:

ECLS in Sepsis

Contraindications

The Pediatric ECLS Circuit:

Patient Management

Complications

Weaning and Decannulation

Outcome and Followup

ECLS Termination

Summary

References

20 Pediatric Cardiac Extracorporeal Life Support

Introduction

Technical Aspects

Indications and Outcomes

ECMO in Patients With Functionally Univentricular Circulation

Outcome and Risk Factors for Death

Conclusions

References

21 Adult Respiratory ECMO

Introduction

Evidence base

Case Selection

Transport

Cannulation

Circuit design

Treatment Protocols

The ECMO Specialist and Nursing Care

Results

Conclusion

References

22 Adult Cardiac Support

Introduction

Options for Temporary Mechanical Circulatory Support

Weaning

Results

Summary

References

23 Extracorporeal Cardiopulmonary Resuscitation: ECPR

Definition

Patient Selection

Technical Issues

Outcomes

Future Directions

References

IV: Other Uses for ECLS

24 Ventricular Assist Devices in Children

Introduction

Types of Ventricular Assist Devices

ECMO to Bridge Children to Cardiac Transplantation

ECMO versus VAD as Initial Device for Bridge to Transplantation

Transition of ECMO patients to VAD

Ventricular Assist Device Use in Single Ventricle Patients

Ventricular Assist Device Anticoagulation

Conclusion

References

25 Plasmapheresis

Introduction

Historical Perspective

Physiology

Apheresis Procedure

Selected Indications for Plasmapheresis

Apheresis in the ECMO patient

Specific humoral considerations of Therapeutic Apheresis

Care of the apheresis patient

Complications

References

26 Artificial Lung

Introduction

History of Artificial Lung Development

Design and Application of an Artificial Lung

Applications for an Artificial Lung

References

27 Extracorporeal Support Assisted Organ Donation

Introduction

Rapid Recovery for procuring organs of Donors after Cardiac Death (DCD)

ECS assisted DCD technique

ECS of Maastricht type III DCD

EDCD compared to RR

Outcome of organs transplanted from ECS assisted DCD

ECS of Maastricht type I and II DCD

ECS assist for brain dead donors

Laboratory Experience

Future Directions

Conclusion

References

28 Sepsis and ECMO

Introduction

Indications

Contraindications

Cannulation

Management on ECMO

Outcomes

Conclusions

References

29 Extracorporeal Life Support Pre and Post Lung Transplantation

Abstract

Introduction

ECLS Pre-Lung Transplantation

Modes of ECLS–Configuration of Device

Hypercapnic Respiratory Failure

Hypoxemic Respiratory Failure

Hypoxemic Respiratory Failure and Hemodynamic Compromise

Pulmonary Hypertension and Right Ventricular Failure

Patient Management

Outcomes

Perioperative ECLS

ECLS Post Lung Transplantation

Conclusions

References

30 Cardiac Catheterization Procedures for ECMO Patients

Introduction

Left Heart Decompression on ECMO

ECMO to Support High Risk Cardiac Catheterization Procedures

Summary

References

31 The Future of Extracorporeal Life Support

References

V: Logistics and Legalitites of ECLS

32 Regionalization and Triage

Which centers should provide ECMO?

The benefits of regionalization

Volume-outcome benefits

Regionalized systems of care

Recommendation

Triage of patients for ECMO

References

33 Transport of the ECMO Patient: From Concept to Implementation

Introduction

History of inter-hospital ECMO transport

Logistics of inter-hospital transport

Effects of altitude on membrane gas exchange

Recognition and management of in-transport emergencies

Military ECMO transport and lessons from combat casualty care

Results of inter-hospital transport

Intra-hospital transport

Conclusions

Disclaimer

Acknowledgment

References

34 ECMO Administrative and Training Issues, and Sustaining Quality

Introduction

Essential Hospital Support Components

ECMO Team Organization

Educational Process

Maintaining Competency Standards

Summary

References

35 Economics of ECLS

Introduction

Costs

Charges and reimbursement

Intangible costs and benefits of ECMO

Is it worth it?

References

36 Regulatory and Legal Aspects of ECLS

Introduction

Summary of the statutory authority of the FDA for medical devices

Device classification

Regulatory approval process

Regulatory processes for marketing ECLS devices

Issues with ECLS devices

Implications of using an ECLS device off-label

Is ECLS/ECMO FDA approved?

The legal process

Civil liability

Informed consent

The rules of research

Legal implications as ECMO develops

Conclusion

References

37 ECMO Ethics in the Twenty-first Century

Introduction

Two Typical ECMO scenarios

Best interest standard

Substituted judgment

Emotions

ECMO and futility

Defining time-limited trials

Palliative care

Conclusions

References

Glossary